Revolutionizing Biaryl Synthesis: The Lithium-Element Exchange Method

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[258, 259] un échange iode/lithium est réalisé. Jul 21, 2022 · herein, we report the flow microsynthesis of functionalized biaryls by integrating lithiation, zincation, and coupling reactions mediated by functionalized aryl zinc. The resulting biphenyllithiums could be trapped with various.

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