Isaac's Dice Room: The Most Effective Item Combinations

(rerolls all held items, pickups, trinkets, and pedestal items) Dice rooms are special rooms that can randomize many elements of the run. Dice rooms require two keys to be opened, unlike most other special rooms.

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For a dice room to spawn, two things must happen; First, the game must decide that a sacrifice room will spawn that floor. Dice rooms in the binding of isaac are unique spaces that offer players strategic advantages throug Has anyone gotten some insanely strong item combinations so far?

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1) the ludovico technique + technology this creates a pretty large, controllable laser circle on the ground. Anything that touches this, recieves damage multiple times per second. Bosses died within a few seconds. 2) tammys head + brimstone this really takes the cake. 4 and 5 are by far the best ones but i guess room 4 since that one is always nice.

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