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Depending on the dice roll on the floor there is different effects. If you're having an amazing run and find a dice room that you don't know the effet of, i'd be careful, it may shuffle you to worse items. Dice rooms are special rooms that can randomize many elements of the run.
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Dice rooms require two keys to be opened, unlike most other special rooms. For a dice room to spawn, two things must happen; First, the game must decide that a sacrifice room will spawn that floor. If i'm checking dice rooms, i'm pretty much exclusively looking for a 5 room.
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5 is always helpful unless you're trying to play fast (in which case you're probably not checking dice rooms), vs all the others being either highly situational or just straight up bad. 5 is pretty good. What are dice rooms in the binding of isaac: It should first be noted that dice rooms are tied to sacrifice rooms. To elaborate, in order for a dice room to spawn, a sacrifice room must be spawned, first.
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