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Still, given the current climate of fear around opioids, many patients and doctors are looking for alternatives, and there are some, each with its own list of pros, cons and efficacy. A systematic review of experimental pain studies showed that patients with oud on opioid agonist therapy (oat) have had doses of opioid analgesics titrated to as much as 20 times the doses. To examine, among individuals with pain seeking bnt for opioid dependence, the use of pain treatment modalities, perceived efficacy of prior pain treatment, and interest in pursuing pain.
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